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Sodium (5-Sulfonatopentyl) Methanethiosulfonate

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Product Information

Chemical Data

Analyte Name

Sodium (5-Sulfonatopentyl) Methanethiosulfonate

CAS Number

385398-80-1

Molecular Formula

C6 H13 O5 S3 . Na

Molecular Weight

284.35

Accurate Mass

283.9823

SMILES

[Na+].CS(=O)(=O)SCCCCCS(=O)(=O)[O-]

InChI

InChI=1S/C6H14O5S3.Na/c1-13(7,8)12-5-3-2-4-6-14(9,10)11;/h2-6H2,1H3,(H,9,10,11);/q;+1/p-1

IUPAC

sodium;5-methylsulfonylsulfanylpentane-1-sulfonate

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease.

References: Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997)

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