Product Code
TRC-P700745
CAS Number
EP Description
Pramipexole EP Impurity D
USP Description
Pramipexole USP Related Compound D
Product Format
Neat
Molecular Formula
C10 H17 N3 S . 2 Cl H
Molecular Weight
284.25
API Family
PramipexoleProduct Categories
Alternate CAS Number
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Analyte Name
(R)-Pramipexole-Dihydrochloride
CAS Number
104632-27-1
Molecular Formula
C10 H17 N3 S . 2 Cl H
Molecular Weight
284.25
Accurate Mass
283.0677
SMILES
NC1=NC(CC[C@](N)(CCC)C2)=C2S1.[H]Cl.[H]Cl
InChI
InChI=1S/C10H17N3S.2ClH/c1-2-4-10(12)5-3-7-8(6-10)14-9(11)13-7;;/h2-6,12H2,1H3,(H2,11,13);2*1H/t10-;;/m1../s1
IUPAC
(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;dihydrochloride
Alternate CAS Number
Free base: 104632-28-2
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
API Family
(R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.
References: Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)
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