Product Code
TRC-H656560
CAS Number
Product Format
Neat
Molecular Formula
C11 H19 N O5
Molecular Weight
245.27
Product Categories
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Analyte Name
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-butyl ester 2-methyl ester
CAS Number
74844-91-0
Molecular Formula
C11 H19 N O5
Molecular Weight
245.27
Accurate Mass
245.1263
SMILES
COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C
InChI
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
IUPAC
1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
Storage Temperature
+4°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.
References: Freer, R., et al.: Biochemistry, 21, 257 (1982), Higgins, J., et al.: J. Med. Chem., 39, 1013 (1996), Cavicchioni, G., et al.; Bioorg. Chem., 34, 298 (2006), Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (2006),
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