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2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate

Product Code

TRC-F510000

CAS Number

351330-42-2

Product Format

Neat

Molecular Formula

C24 H19 N O8 S2

Molecular Weight

513.54

Product Categories

TRC, Fluorescent probes

Price and availability

48-hour USA dispatch time
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Product Information

Chemical Data

Analyte Name

2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate

CAS Number

351330-42-2

Molecular Formula

C24 H19 N O8 S2

Molecular Weight

513.54

Accurate Mass

513.0552

SMILES

CS(=O)(=O)SCCC(=O)Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35

InChI

InChI=1S/C24H19NO8S2/c1-35(30,31)34-9-8-22(28)25-13-2-5-17-16(10-13)23(29)33-24(17)18-6-3-14(26)11-20(18)32-21-12-15(27)4-7-19(21)24/h2-7,10-12,26-27H,8-9H2,1H3,(H,25,28)

IUPAC

N-(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)-3-methylsulfonylsulfanylpropanamide

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

A thiol specific fluorescent probe useful for ion channel and protein topology research. The recently available MTS-fluorophores may find application in the real-time monitoring of conformational changes, since fluorophores coupled to introduced cysteines can change their fluorescence during a conformational change. Fluorescence lifetime may also yield information regarding distances and molecular motion in a protein molecule.Fluorescence: max. Abs. 492nm; max. Em. 515nm; e x 10-3: 75

References: Mannuzzu, L.M., et al.: Science, 271, 213 (1996), Goulett, C.C., et al.: JBC, 273, 45, 30012 (1998), Adams, C.M., et al.: JBC, 273, 46, 30204 (1998)
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