C6 Ceramide-13C2,d2
Product Code
TRC-C262602
Product Format
Neat
Molecular Formula
C2213C2H45D2NO3
Molecular Weight
401.63
Product Categories
TRC, Stable isotopes, Stable Isotope Labelled Analytical Standards
Product Type
Stable Isotope LabelledUnlabelled CAS Number
Purity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
C6 Ceramide-13C2,d2
Molecular Formula
C2213C2H45D2NO3
Molecular Weight
401.63
SMILES
CCCCCCCCCCCCC/C=C/[C@@H](O)[13C@@H](NC(CCCCC)=O)[13C]([2H])([2H])O
Unlabelled CAS Number
124753-97-5
SIL Type
Carbon, Deuterium
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
Product Description
A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
References: Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),