A77 1726-d4
Product Code
TRC-A771727
CAS Number
Product Format
Neat
Molecular Formula
C12 2H4 H5 F3 N2 O2
Molecular Weight
274.23
API Family
LeflunomideProduct Categories
TRC, Enzyme activators, Immunosuppressants, Immunosuppressants, Immunosuppressants, Immunosupressants, Stable isotopes, Stable Isotope Labelled Analytical Standards, Cancer Research Chemicals and Analytical Standards
Unlabelled CAS Number
Purity
>95% (HPLC)
Drug Type
Immunosuppressants
Documentation
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Product Information
Chemical Data
Analyte Name
A77 1726-d4
CAS Number
1185240-22-5
Molecular Formula
C12 2H4 H5 F3 N2 O2
Molecular Weight
274.23
Accurate Mass
274.0867
SMILES
[2H]c1c([2H])c(c([2H])c([2H])c1NC(=O)C(=C(C)O)C#N)C(F)(F)F
InChI
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/i2D,3D,4D,5D
IUPAC
2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide
Unlabelled CAS Number
163451-81-8
SIL Type
Deuterium
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Metabolite; Stable Isotope Labelled
Product Format
Neat
API Family
Purity
>95% (HPLC)
Product Description
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.
References: Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)