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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-13C2,15N

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Product Information

Chemical Data

Analyte Name

Acadesine 13C2,15N

CAS Number

1609374-70-0

Molecular Formula

13C2 C7 H14 15N N3 O5

Molecular Weight

261.21

Accurate Mass

261.1002

SMILES

N[13c]1[13c]([15n]cn1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N

InChI

InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1/i4+1,7+1,12+1

IUPAC

5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl](4,5-^{13}C_{2},3^{15}N)imidazole-4-carboxamide

Alternate CAS Number

2627-69-2

SIL Type

Nitrogen, Carbon

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

Stable Isotope Labelled

Product Format

Neat

HPLC Purity

>95%

Analytical Method

NMR, HPLC, MS

Product Description

A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.

References: Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

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