Mesna-d4 (contain disulfide)
Product Code
TRC-M225752
CAS Number
Product Format
Neat
Molecular Formula
C2 D4 H Na O3 S2
Molecular Weight
168.204
Product Categories
Anticancerous, Additional Cancer Bioactive Molecules, Stable isotopes, TRC, Stable isotopes, Stable Isotope Labelled Analytical Standards
Unlabelled CAS Number
Documentation
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Product Information
Product Data
Analyte Name
Mesna-d4
CAS Number
1189479-73-9
Molecular Formula
C2 D4 H Na O3 S2
Molecular Weight
168.204
Accurate Mass
167.983
SMILES
[2H]C([2H])(S)C([2H])([2H])S(=O)(=O)O[Na]
InChI
InChI=1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1/i1D2,2D2;
IUPAC
(1,1,2,2-tetradeuterio-2-sulfanylethyl)sulfonyloxysodium
Unlabelled CAS Number
19767-45-4
SIL Type
Deuterium
Storage & Transport Information
Storage Temperature
+4°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Attributes
Product Type
Metabolite; Stable Isotope Labelled
Product Format
Neat
Product Description
Mesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.
References: Tekeres, M., et al.: Clin. Ther., 4, 56 (1981), Brock, N., et al.: Eur. J. Cancer Clin Oncol., 18, 1377 (1982), James, C.A., et al.: Br. J. Clin. Pharmacol., 23, 561 (1987), Schoenike, S.E., et al.: Clin. Pharm., 9, 179 (1990),
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