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Lubiprostone-d7

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48-hour USA dispatch time
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Product Information

Chemical Data

Analyte Name

Lubiprostone-d7

CAS Number

1217675-13-2

Molecular Formula

C20H25D7F2O5

Molecular Weight

397.51

SMILES

O=C(C(F)(F)CC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])CC[C@@H]1[C@@H](CCCCCCC(O)=O)C(C[C@H]1O)=O

Unlabelled CAS Number

136790-76-6

SIL Type

Deuterium

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

Stable Isotope Labelled; Metabolite; API

Product Format

Neat

API Family

Lubiprostone

Product Description

Labelled Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.

References: Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001), Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003),

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