Product Code
TRC-S692060
CAS Number
Product Format
Neat
Molecular Formula
C7 H10 O4
Molecular Weight
158.1519
Product Categories
TRC, Carbohydrate derivatives, Additional pharmaceutical toxicology research materials
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Analyte Name
Succinylacetone
CAS Number
51568-18-4
Molecular Formula
C7 H10 O4
Molecular Weight
158.1519
Accurate Mass
158.0579
SMILES
CC(=O)CC(=O)CCC(=O)O
InChI
InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)
IUPAC
4,6-dioxoheptanoic acid
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.
References: Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813
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