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Topotecan-d6

Product Code

TRC-T542502

CAS Number

1044904-10-0

Product Format

Neat

Molecular Formula

C23 2H6 H17 N3 O5

Molecular Weight

427.48

API Family

Topotecan

Unlabelled CAS Number

123948-87-8

Price and availability

48-hour USA dispatch time
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Product Information

Chemical Data

Analyte Name

Topotecan-d6

CAS Number

1044904-10-0

Molecular Formula

C23 2H6 H17 N3 O5

Molecular Weight

427.48

Accurate Mass

427.2014

SMILES

[2H]C([2H])([2H])N(Cc1c(O)ccc2nc3C4=CC5=C(COC(=O)[C@]5(O)CC)C(=O)N4Cc3cc12)C([2H])([2H])[2H]

InChI

InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1/i2D3,3D3

Unlabelled CAS Number

123948-87-8

SIL Type

Deuterium

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

API; Stable Isotope Labelled

Product Format

Neat

API Family

Topotecan

Product Description

Labelled Topotecan (T542500). A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.

References: Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990), BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991), Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992),

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