2-Aminoethyl Methanethiosulfonate Hydrochloride
Product Code
TRC-A609150
CAS Number
Product Format
Neat
Molecular Formula
C3 H9 N O2 S2 . Cl H
Molecular Weight
191.70
Product Categories
TRC, GABA receptors, Addiction, Neurotransmission, Nociception, Alzheimer's, Depression, Epilepsy, Memory, Learning and Cognition, Parkinson's, Schizophrenia, Sleep, Stress and Anxiety, Stroke, Pain and Inflammation
HPLC Purity
>95%
Documentation
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Product Information
Chemical Data
Analyte Name
2-Aminoethyl Methanethiosulfonate, Hydrochloride
CAS Number
37597-96-9
Molecular Formula
C3 H9 N O2 S2 . Cl H
Molecular Weight
191.70
Accurate Mass
190.9841
SMILES
Cl.CS(=O)(=O)SCCN
InChI
InChI=1S/C3H9NO2S2.ClH/c1-8(5,6)7-3-2-4;/h2-4H2,1H3;1H
IUPAC
2-methylsulfonylsulfanylethanamine;hydrochloride
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
HPLC Purity
>95%
Product Description
Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References: Xu, M. & Akabus, M.H.: J. Biol. Chem., 268, 21505 (1993), Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996); Frillingos, S., & Kaback, H.R.: Biochem., 35, 3950 - 3956 (1996)
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