Rosuvastatin Lactone
Product Code
TRC-R700550
CAS Number
EP Description
Rosuvastatin Calcium Impurity D
Product Format
Neat
Molecular Formula
C22 H26 F N3 O5 S
Molecular Weight
463.52
Product Categories
TRC, Impurity Reference Materials , Cardiac drugs and beta blockers, Cardiac drugs and beta blockers, Cardiac drugs and beta blockers
Purity
>95% (HPLC)
Drug Type
Cardiac Drugs
Documentation
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Product Information
Chemical Data
Analyte Name
Rosuvastatin Lactone
CAS Number
503610-43-3
Molecular Formula
C22 H26 F N3 O5 S
Molecular Weight
463.52
Accurate Mass
463.1577
SMILES
CC(C)c1nc(nc(c1\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c3ccc(F)cc3)N(C)S(=O)(=O)C
InChI
InChI=1S/C22H26FN3O5S/c1-13(2)20-18(10-9-17-11-16(27)12-19(28)31-17)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)32(4,29)30/h5-10,13,16-17,27H,11-12H2,1-4H3/b10-9+/t16-,17-/m1/s1
IUPAC
N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Metabolite; Impurity
Product Format
Neat
Impurity Type
Intermediate
API Family
Purity
>95% (HPLC)
Product Description
Rosuvastatin Lactone (Rosuvastatin EP Impurity D) is an intermediate in the production of Rosuvastatin (R700500) derivatives.
References: Martin, P., et al.: Clin. Ther., 25, 2215 (2003),