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4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-(beta)-D-glucopyranoside Potassium Salt

Product Code

TRC-M335000

CAS Number

210357-38-3

Product Format

Neat

Molecular Formula

C18 H20 N O11 S . K

Molecular Weight

497.51

Product Categories

Pharmaceutical Reference Standards, TRC, Oligosaccharides

Purity

>95% (HPLC)

Price and availability

48-hour USA dispatch time
If Exact Weight packaging is selected, a certificate will be delivered with the product, which will indicate the mass of the material dispensed into the vial with a precision of up to 3 decimal places. Exceptions apply.
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Product Information

Chemical Data

Analyte Name

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-beta-D-glucopyranoside Potassium Salt

CAS Number

210357-38-3

Molecular Formula

C18 H20 N O11 S . K

Molecular Weight

497.51

Accurate Mass

497.0394

SMILES

[K+].CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(=O)(=O)[O-])O[C@H]1Oc2ccc3C(=CC(=O)Oc3c2)C

InChI

InChI=1S/C18H21NO11S.K/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/q;+1/p-1/t13-,15-,16-,17-,18-;/m1./s1

IUPAC

potassium;[(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Purity

>95% (HPLC)

Product Description

A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms.

References: Clinical Genetics, 26, 318 (1984); Bayleran, J., et al.: Clin. Chem. Acta 143, 73 (1984)
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