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4-Methylumbelliferyl 2-Acetamido-2-deoxy-beta-D-glucopyranoside

Product Code

TRC-M334000

CAS Number

37067-30-4

Product Format

Neat

Molecular Formula

C18 H21 N O8

Molecular Weight

379.36

Product Categories

TRC, Fluorescent probes, Enzyme substrates

Purity

>95% (HPLC)

Price and availability

48-hour USA dispatch time
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Product Information

Chemical Data

Analyte Name

4-Methylumbelliferyl 2-Acetamido-2-deoxy-beta-D-glucopyranoside

CAS Number

37067-30-4

Molecular Formula

C18 H21 N O8

Molecular Weight

379.36

Accurate Mass

379.1267

SMILES

CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccc3C(=CC(=O)Oc3c2)C

InChI

InChI=1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18-/m1/s1

IUPAC

N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]acetamide

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Purity

>95% (HPLC)

Product Description

Fluorogenic substrate used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms.Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm

References: Biochem. J., 78, 151 (1961)
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