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Product Overview

Product Code

TRC-K162500

CAS Number

142273-20-9

Product Format

Neat

Molecular Formula

C16 H11 Br N2 O

Molecular Weight

327.18

Product Categories

TRC, Chiral catalysts, ligands, & reagents

Product Type

Synthesis Tools

Documentation

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Product Information

Chemical Data

Analyte Name

Kenpaullone

CAS Number

142273-20-9

Molecular Formula

C16 H11 Br N2 O

Molecular Weight

327.18

Accurate Mass

326.0055

SMILES

Brc1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1

InChI

InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)

IUPAC

9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3+? inhibitor (IC50=23nM).

References: Zaharevitz, D.W., et al.: Cancer Res., 59, 2566 (1999), Leclerc, S., et al.: J. Biol. Chem., 276, 251 (2001), Bain, J., et al.: Biochem. J., in press.

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