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Hydroxy Fasudil Hydrochloride

Product Code

TRC-H942380

CAS Number

155558-32-0

Product Format

Neat

Molecular Formula

C14 H17 N3 O3 S . Cl H

Molecular Weight

343.83

Product Categories

TRC

Price and availability

48-hour USA dispatch time
If Exact Weight packaging is selected, a certificate will be delivered with the product, which will indicate the mass of the material dispensed into the vial with a precision of up to 3 decimal places. Exceptions apply.

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Product Information

Chemical Data

Analyte Name

Hydroxyfasudil Hydrochloride

CAS Number

155558-32-0

Molecular Formula

C14 H17 N3 O3 S . Cl H

Molecular Weight

343.83

Accurate Mass

343.0757

SMILES

Cl.Oc1nccc2c(cccc12)S(=O)(=O)N3CCCNCC3

InChI

InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H

IUPAC

5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-ol;hydrochloride

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.

References: Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),
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