6-Cyano-7-nitroquinoxaline-2,3-dione
Product Code
TRC-C982000
CAS Number
Product Format
Neat
Molecular Formula
C9 H4 N4 O4
Molecular Weight
232.15
Product Categories
Purity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
6-Cyano-7-nitroquinoxaline-2,3-dione
CAS Number
115066-14-3
Molecular Formula
C9 H4 N4 O4
Molecular Weight
232.15
Accurate Mass
232.0233
SMILES
[O-][N+](=O)c1cc2NC(=O)C(=O)Nc2cc1C#N
InChI
InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
IUPAC
7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
Product Data
Storage Temperature
+4°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
Product Description
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively.
References: Honore, et al. Science, 241, 701 (1988),Haas, H.S., et al.: Int. J. Oncol., 27, 867 (2005), Kobayashi, K., et al.: J. Pharmacol. Sci., 108, 517 (2008), Shabat-Simon, M., et al.: J. Neurosci., 28, 8406 (2008), Cruz, L.A., et al.: J. Med. Chem., 51, 5856 (2008),