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C6 Ceramide-13C2,d2

Product Code

TRC-C262602

Product Format

Neat

Molecular Formula

C2213C2H45D2NO3

Molecular Weight

401.63

Product Categories

TRC, Stable isotopes, Stable Isotope Labelled Analytical Standards

Product Type

Stable Isotope Labelled

Unlabelled CAS Number

124753-97-5

Purity

>95% (HPLC)

Price and availability

48-hour USA dispatch time
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Product Information

Chemical Data

Analyte Name

C6 Ceramide-13C2,d2

Molecular Formula

C2213C2H45D2NO3

Molecular Weight

401.63

SMILES

CCCCCCCCCCCCC/C=C/[C@@H](O)[13C@@H](NC(CCCCC)=O)[13C]([2H])([2H])O

Unlabelled CAS Number

124753-97-5

SIL Type

Carbon, Deuterium

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Purity

>95% (HPLC)

Product Description

A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.

References: Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),
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