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Product Overview

Product Code

TRC-A603150

CAS Number

209977-56-0

Product Format

Neat

Molecular Formula

2 C9 H12 N2 O6 . 3 H2 O

Molecular Weight

542.45

Product Categories

Glutamate receptors, TRC, Addiction, Neurotransmission, Alzheimer's, Depression, Huntington's, Epilepsy, Memory, Learning and Cognition, Multiple Sclerosis, Parkinson's, Schizophrenia, Stress and Anxiety, Stroke, Pain and Inflammation, API Reference Standards & Research Materials

Product Type

API

Product Information

Chemical Data

Analyte Name

(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]

CAS Number

209977-56-0

Molecular Formula

2 C9 H12 N2 O6 . 3 H2 O

Molecular Weight

542.45

Accurate Mass

542.1708

SMILES

O.O.O.Cc1onc(OCC(=O)O)c1CC(N)C(=O)O.Cc2onc(OCC(=O)O)c2CC(N)C(=O)O

InChI

InChI=1S/2C9H12N2O6.3H2O/c2*1-4-5(2-6(10)9(14)15)8(11-17-4)16-3-7(12)13;;;/h2*6H,2-3,10H2,1H3,(H,12,13)(H,14,15);3*1H2

IUPAC

2-amino-3-[3-(carboxymethoxy)-5-methyl-1,2-oxazol-4-yl]propanoic acid;trihydrate

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations relative to kainate-, quisqualate- and NMDA-induced responses.

References: Frandsden, A., et al.: J. Neurochem., 55, 1821 (1990), Krogsgaard-Larsen, P., et al.: J. Med. Chem., 34, 123 (1991), Berg, M., et al.: Acta Neuropathalogica, 81, 255 (1991)

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(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate

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