Product Information
Chemical Data
Analyte Name
2-Amino-5-bromopyrazine-3-carboxylic Acid, Methyl Ester
CAS Number
6966-01-4
Molecular Formula
C6 H6 Br N3 O2
Molecular Weight
232.03
Accurate Mass
230.9643
SMILES
COC(=O)c1nc(Br)cnc1N
InChI
InChI=1S/C6H6BrN3O2/c1-12-6(11)4-5(8)9-2-3(7)10-4/h2H,1H3,(H2,8,9)
IUPAC
methyl 3-amino-6-bromopyrazine-2-carboxylate
Product Data
Storage Temperature
+4°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Product Description
2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is used as the starting material in the preparation of pyrazine derivatives that are AxI and c-Met receptor enzyme inhibitors. These inhibitors are useful in the treatment of tumors. 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is also used in the preparation of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.
References: Rushton, L.; et al.: PCT Int. Appl. 119 pp. Patent 2009 CODEN:PIXXD2; Charrier, J-D.; et al.: J. Med. Chem, 54, 2320 (2011)
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