Product Code
TRC-D477850
CAS Number
Product Format
Neat
Molecular Formula
C10 H10 N4 O2
Molecular Weight
218.21
Product Categories
Enzyme activators, TRC, Enzyme agonists & antagonists, Adenosine receptors, Huntington's, Parkinson's, Sleep, Stroke
Purity
>95% (HPLC)
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Analyte Name
3,7-Dimethyl-1-propargylxanthine
CAS Number
14114-46-6
Molecular Formula
C10 H10 N4 O2
Molecular Weight
218.21
Accurate Mass
218.0804
SMILES
CN1C(=O)N(CC#C)C(=O)c2c1ncn2C
InChI
InChI=1S/C10H10N4O2/c1-4-5-14-9(15)7-8(11-6-12(7)2)13(3)10(14)16/h1,6H,5H2,2-3H3
IUPAC
3,7-dimethyl-1-prop-2-ynylpurine-2,6-dione
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11-¦ 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 -¦ 4 uM.
References: Alfinito, P., et al.: J. Neurosci., 23, 10982 (2003), Golembiowska, K., et al.: Neuropharmacol., 47, 414 (2004), Solinas, M., et al.: Psychopharmacol., 179, 576 (2005),
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