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Product Overview

Product Code

TRC-E945400

CAS Number

159351-69-6

EP Description

Everolimus EP Impurity C

Product Format

Neat

Molecular Formula

C53 H83 N O14

Molecular Weight

958.22

API Family

Everolimus

Product Categories

Pharmaceutical Reference Standards, TRC, Enzyme inhibitors, Immunosuppressants, Immunosuppressants, API Reference Standards & Research Materials, Cytokine and Growth Factor Signalling Modulators, Immunosuppressants, Additional Neuro Products

Product Type

API

Drug Type

Immunosuppressants

Documentation

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Product Information

Chemical Data

Analyte Name

Everolimus

CAS Number

159351-69-6

Molecular Formula

C53 H83 N O14

Molecular Weight

958.22

Accurate Mass

957.5814

Flash Point

-20

SMILES

C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC

InChI

InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Tariff Code

29349990

Product Type

API

Product Format

Neat

API Family

Everolimus

Product Description

Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.

References: Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),

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