Deoxymannojirimycin Hydrochloride
Product Code
TRC-D240000
CAS Number
Product Format
Neat
Molecular Formula
C6 H13 N O4 . Cl H
Molecular Weight
199.63
Product Categories
TRC, Enzyme inhibitors, Glucosamines, Inhibits an enzyme, Enzyme inhibitors, Additional Neuro Products, Aminoglycosides
Alternate CAS Number
Purity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
Deoxymannojirimycin, Hydrochloride
CAS Number
73465-43-7
Molecular Formula
C6 H13 N O4 . Cl H
Molecular Weight
199.63
Accurate Mass
199.0611
SMILES
Cl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4-,5-,6-;/m1./s1
IUPAC
(2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride
Alternate CAS Number
Free base: 84444-90-6
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
Product Description
Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.
References: Eur. J. Biochem., 150, 41-46 (1985), J. Biol. Chem., 261, 4766 (1986), Seftor, R.E.B., et al.: Melanoma Res., 1, 43 (1991), Suzuki, S.S., et al.: J. Cell. Biochem., 51, 181 (1993)