D-erythro-Sphingosine-1-phosphate-13C2,D2
Product Code
TRC-S681502
Product Format
Neat
Molecular Formula
C1613C2H36D2NO5P
Molecular Weight
383.47
Product Categories
TRC, Enzyme inhibitors, Glycerolipids, Glycerophospholipids, Lipids & fatty acids, Glycerolipids, Glycerophospholipids, Lipids & fatty acids, Kinase Modulators, Stable isotopes, Kinase C, Memory, Learning and Cognition, Stable isotopes, Stable Isotope Labelled Analytical Standards
Product Type
Stable Isotope LabelledUnlabelled CAS Number
Documentation
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Product Information
Chemical Data
Analyte Name
D-erythro-Sphingosine-1-phosphate-13C2,D2
Molecular Formula
C1613C2H36D2NO5P
Molecular Weight
383.47
SMILES
N[13C@]([C@H](O)/C=C/CCCCCCCCCCCCC)([H])[13C]([2H])([2H])OP(O)(O)=O
Unlabelled CAS Number
26993-30-6
SIL Type
Deuterium, Carbon
Product Data
Storage Temperature
-20°C
Shipping Temperature
Blue Ice
Country of Origin
CANADA
Product Type
Stable Isotope Labelled
Product Format
Neat
Product Description
A labelled putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes; mobilizes intracellular calcium stores; decreases cellular cAMP; activates phospholipase D; does not inhibitprotein kinase C.
References: Zhang, H., et al.: J. Cell Biol., 114, 155 (1991) Sadahira, Y., et al.: Proc. Natl. Acad. Sci. USA (1992), Cuvillier, O., et al.: Nature, 381, 800 (1996)
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