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Zaprinast

Product Code

TRC-Z150000

CAS Number

37762-06-4

Product Format

Neat

Molecular Formula

C13 H13 N5 O2

Molecular Weight

271.27

Product Categories

TRC

HPLC Purity

>95%

Price and availability

48-hour USA dispatch time
If Exact Weight packaging is selected, a certificate will be delivered with the product, which will indicate the mass of the material dispensed into the vial with a precision of up to 3 decimal places. Exceptions apply.

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Documentation

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Product Information

Chemical Data

Analyte Name

Zaprinast

CAS Number

37762-06-4

Molecular Formula

C13 H13 N5 O2

Molecular Weight

271.27

Accurate Mass

271.1069

SMILES

CCCOc1ccccc1C2=NC(=O)c3[nH]nnc3N2

InChI

InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)

IUPAC

5-(2-propoxyphenyl)-1,4-dihydrotriazolo[4,5-d]pyrimidin-7-one

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

HPLC Purity

>95%

Product Description

A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.

References: Burns, F., et al.: Biochem. J., 238, 487 (1992), Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992),
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